We observed no biased expression of the poor- and good-prognosis-associated genes, according to the KRT18 expression levels, suggesting that there is no differentiation of the HCV-infected Huh7.5.1dif cells to form either parenchymal- or NPC-like subpopulation with differential expression of the poor- or good-prognosis-associated PLS genes (Supplementary Fig. 5f). The gene discussed is KRT18; the disease is nasopharyngeal carcinoma.