FABP4 and acute lymphoblastic leukemia: Unexpectedly, we found that ALL-MSCs had a significantly enhanced capacity for adipogenic differentiation (2.87 ± 0.29-fold increase; n = 7; ***p = 0.0003), as determined by cell staining for adipocyte-specific fatty acid binding 4 (FABP4) (Fig. 2c), without any reciprocal disturbance in osteogenesis (Fig. 2d), indicating that ALL pathogenesis significantly affects the lineage priming of MSCs in an adipocyte-biased manner.