IL6 and Sepsis: More recently, others have shown a close clinical correlation between early HDL-C levels in sepsis and severity of organ failure or survival [27, 28], that HDL-C levels correlate inversely with pro-inflammatory cytokines including TNF-α, IL-6, IL-10 [28], and that cholesterol levels three days after sepsis admission do not return to pre-sepsis baseline levels [29].