The target sequences (CAGCCUC) of miR-485-5p and MYO6 are exhibited in Fig. 4A. TCGA-COAD (colon adenocarcinoma) and READ (rectum adenocarcinoma) analysis show the overexpression of MYO6 in CRC tumors (http://www.cancer.gov/tcga) (Figure S1B). The gene discussed is MYO6; the disease is colon adenocarcinoma.