Furthermore, RNA immunoprecipitation assays suggested the recognition and binding of IGF2BP1 with LBX2-AS1 mRNA in CRC cells (Fig. 3F), proposing that METTL3 induced LBX2-AS1 m6A hypermethylation to enhance its mRNA stability in CRC. The gene discussed is LBX2-AS1; the disease is colorectal carcinoma.