IFNA5 and lobular neoplasia: To investigate the potential capacity of circ_0007059, miR-1278, and SHP-1 in preventing or treating LN, Lentiviral-circ_0007059, miR-1278 mimic and SHP-1 were administered to IFNα5 adenovirus-treated (NZB × NZW)F1 mice via tail vein injection.