The cell densities of BrdU+Olig2+Nestin+ cells at P25 were 1.77 ± 0.36 cells/ 106 μm3 and 4.48 ± 0.43 cells/ 106 μm3 for control and BE mice, respectively (one-way ANOVA, F(1, 8) = 22.96, p = 0.0014). This evidence concerns the gene OLIG2 and Barrett esophagus.