The number of patients who had diabetic ketoacidosis (DKA) and/or required insulin treatment was significantly higher in the 3-Screen positive group than in the 3-Screen negative group (37% vs 17%, respectively, for patients with DKA, P < 0.05 and 43% vs 25%, respectively, for patients on insulin treatment, P < 0.05). Here, INS is linked to diabetic ketoacidosis.