Among 92 infants with HL passing limited genetic screening, expanded genetic screening further detected 17 infants (18.5%) with a variation (Table 1), including more nsHL genes (eg, LOXHD1, TECTA, and CCDC50) and sHL genes (eg, ADGRV1, CHD7, and FGFR2). The gene discussed is LOXHD1; the disease is Hodgkins lymphoma.