Likewise, no significant correlations between anti-Hsp90 IgE serum levels and SCORAD (− 0.020, p = 0.914) as well as serum levels of total IgE (0.216, p = 0.258) and the presence of comorbidities such as asthma (− 0.086, p = 0.654), allergic rhinitis (− 0.074, p = 0.700), or allergic conjunctivitis (0.057, p = 0.765) could be recorded. The gene discussed is IGHE; the disease is asthma.