Analyses of splenic lymphoid (CD4+, CD8+ and γδ T cells, natural killer (NK), NK1.1+ NKT cells) and myeloid cells (CD11b+ Ly6G+ neutrophils, MHC class IIhi CD11chi dendritic cells, F4/80+ CD11b− red pulp macrophages, CD11b− CD169+ marginal metallophilic macrophages, CD11b− MARCO+ marginal zone macrophages, or CD11b+ Ly6C+ CCR2+/− monocytes) by flow cytometry at these timepoints indicated that there were no significant differences in the numbers of any major splenic cell population between RMT- and SBP-initiated infections. Here, MARCO is linked to infection.