Although the numbers of splenic IFNγ-producing NK, NK1.1+ NKT, γδ T cells and αβ T cells observed here in RMT and SBP P. chabaudi infections within the first 7 days of infection were similar, our comparative transcriptome analysis showed small but consistently higher expression levels of a number of irf genes, such as irf1, which mediates signalling of type I/II IFNs, and regulates antigen-presentation, and irf7 which is a master regulator of Type I IFN (Negishi et al., 2018). The gene discussed is IRF7; the disease is infection.