In univariate analysis, cirrhosis, HE grades, infection, ascites, gastrointestinal bleeding, WBC, TB, INR, BUN, ALT, PLT, hemoglobin, Scr, NLR, Na, K, ALB, MELD, and MELD-Na showed a significant positive correlation with 90-day transplant-free mortality (p < 0.05) (data not shown). The gene discussed is ALB; the disease is hereditary elliptocytosis.