Similarly, we found similar results in Transwell assay, wound healing assay and EMT marker detection, that is, overexpression of HHIP can partially reversed the migration of miR-199b-5p in GC cells and EMT process(Figures 7A–I).These results suggested that miR-199b-5p promoted the proliferation, migration and EMT process of GC cells by directly targeting HHIP. This evidence concerns the gene HHIP and gastric cancer.