TLR3 and neoplasm: The mRNA and protein expression of TLR3 in different subgroups of patients with KIRC was analysed, which revealed an increased TLR3 mRNA expression in patients with KIRC compared with the healthy controls based on race, gender, age, subtypes, tumour grade, cancer stages, and nodal metastasis status (see Figure 7, all p < 0.05).