Elevations in IFN-γ, IL6, IL8, soluble interleukin 2 receptor (sIL2R)-α, sgp130, soluble IL6 receptor (sIL6R), MCP1, MIP1α, MIP1β, and granulocyte-macrophage colony-stimulating factor (GM-CSF) were noted in ALL recipients of IECT who developed severe CRS (52). This evidence concerns the gene CSF2 and congenital rubella syndrome.