Elevations in IFN-γ, IL6, IL8, soluble interleukin 2 receptor (sIL2R)-α, sgp130, soluble IL6 receptor (sIL6R), MCP1, MIP1α, MIP1β, and granulocyte-macrophage colony-stimulating factor (GM-CSF) were noted in ALL recipients of IECT who developed severe CRS (52). The gene discussed is CSF2; the disease is acute lymphoblastic leukemia.