CD8A and colorectal adenocarcinoma: The association between PARP1 alterations and immune infiltrates in different tumors was showed in Figure 3A, and then PARP1 altered group was substantially correlated with higher immune infiltrates across several tumors, including CD8+ T cells in colorectal adenocarcinoma (P = 0.0061), endometrial carcinoma (P = 0.0033), stomach cancer (P = 0.033), and cervical cancer (P = 0.026) (Figures 3B–E).