The frequency of CD86+ cells and CD40+ cells was also reduced in E. rectale (1.0x109 C.F.U/mice)-treated BD mice compared to BDN mice (4.60 ± 2.0% vs. 12.45 ± 4.62%, p = 0.05; 19.16 ± 3.88% vs. 34.27 ± 6.20%, p = 0.05, respectively) (Figure 6F, G). The gene discussed is CD40; the disease is Behcet disease.