IL6 and COVID-19: RNA sequencing analysis of cell and animal models of SARS-CoV-2 infection, blood, lung, and airway biopsies from COVID-19 patients showed inflammatory responses characterized by low levels of type I and III IFNs, increased interleukin-6 (IL-6), and a variety of chemokines (Blanco-Melo et al., 2020; Daamen et al., 2021).