IL33 and Insulin resistance: Similarly, in diet-induced obese mice, IL-33 expansion of ST2+ Treg cells reduces inflammation in visceral adipose tissue ameliorating insulin resistance [70], and in the eye retinal inflammation in the experimental autoimmune uveitis (EAU) model is attenuated by IL-33 expansion of Th2 cells and reduction of pathogenic Th17 inflammatory cells [36].