Cluster B contained numerous genes involved in cell cycle regulation such as CCND1 and E2F1, and DNA replication such as RAD51, DNA damage (DNA repair, transcriptional regulation of TP53, and base excision repair), RNA metabolism, kinesins, beta-catenin degradation, generic transcription pathways, and the Fanconi anemia pathway. The gene discussed is TP53; the disease is Fanconi anemia.