The influence of the presence of pets was also significant for rhinitis (p < 0.001), atopic dermatitis (p < 0.001), severity of asthma (p < 0.05), higher IgE levels both for D. pteronyssinus and D. farinae (p < 0.001), and reactivity on other allergens (other than domestic mites (p < 0.001). The gene discussed is IGHE; the disease is asthma.