Similarly, according to the online KM Plotter database40,41, which provides data on their own, large cohort of breast carcinomas regardless of their histological type, high CLDN3 level is associated with shorter DMFS (p = 0.003), while in the KM Plotter database PALS1 and PAR6 showed no significant correlation with DMFS (Fig. 6). This evidence concerns the gene PALS1 and breast carcinoma.