We observed significant upregulation of pro-inflammatory cytokines IL-6 (p-value ≤ 0.029), CXCL8/IL-8 (p-value ≤ 0.009), IL-1β (p-value ≤ 0.041) and IL-2 (p-value ≤ 0.025) in tears of chronic SJS patients when compared to controls. This evidence concerns the gene CXCL8 and Schwartz-Jampel syndrome.