In the same way CXCL10, ELR-negative chemokine is an inhibitor of angiogenesis is down regulated in SJS. Simultaneously, the imbalanced expression of CXCL8/IL-8 and CXCL10 were also observed in other fibro-proliferative disorders i.e., Idiopathic pulmonary fibrosis (IPF)20. The gene discussed is CXCL10; the disease is Schwartz-Jampel syndrome.