Compared to women with non-deficient levels of 25(OH)D (≥50 nmol/L) and normal PTH levels (≤6.89 pmol/L), women with either deficient 25(OH)D levels (<50 nmol/L) or PTH excess (>6.89 pmol/L) had higher BMI, lower physical activity, and higher fasting glucose and insulin and prevalence of diabetes, obesity, and hypertension among both white and black women. The gene discussed is INS; the disease is diabetes mellitus.