EZH2 and Miyoshi myopathy: Gene Set Enrichment Analysis (GSEA) identified, as the most down-regulated pathways, genes involved in cell-cycle, stem cells, proliferating plasmablasts and MM proliferating molecular subgroup together with genes repressed upon loss of the histone H3K27 methyltransferase EZH2 (Figs. 3b and Additional files 2 and 3: Figure S7B).