Here, we found that the expression of sEH was markedly increased at 7, 14, 21, and 28 days after hemorrhagic stroke and reached its highest value at day 14 compared with the sham control (Fig. 2a), which is consistent with the time point when rats developed mechanical allodynia and exhibited a slump of 14,15-EET [24]. The gene discussed is EPHX2; the disease is hemorrhagic stroke.