Another study confirmed the negative correlation between miR-550a-3-5p and YAP1 in colon cancer tissues, and showed that miR-550a-3-5p could repress tumor cell proliferation, metastasis, and sphere formation by directly inhibiting YAP1 and its oncogenic pathway in various cancer cell types [27]. The gene discussed is YAP1; the disease is malignant colon neoplasm.