The univariate Cox analysis revealed that high CDH6 expression was significantly associated with poor overall survival [hazard ratio (HR): 1.305, 95% CI: 1.102–1.544, P = 0.002]; as well as age (HR: 1.023, 95% CI: 1.004–1.044, P = 0.020); stage (HR = 1.451, 95% CI: 1.144–1.841, P = 0.002); and N stage (HR = 1.305, 95% CI: 1.102–1.544, P = 0.002) among GC patients (Fig. 7a). The gene discussed is CDH6; the disease is gastric cancer.