The GABRB3-GABRA5-GABRG3 gene cluster has been the focus of attention for many years, and studies have suggested that it is involved in various psychiatric and neurological diseases with comorbid sleep disorders, such as panic disorder, autism spectrum disorders, Angelman and Prader–Willi syndrome, and epilepsy [24–28]. The gene discussed is GABRG3; the disease is autism spectrum disorder.