Moreover, the transcription expression pattern of S100As family members were further analyzed by UALCAN whose resources were based on publicly available cancer OMICS data (TCGA and MET500), which was different from Oncomine database, and the results indicated that, S100A2/4/6/10/14/16 were over-expressed in PDAC samples compared with normal pancreas samples (Fig. 4). Here, S100A2 is linked to cancer.