We first analyzed the expression of S100A2/4/6/10/14/16 in human pancreatic cancer lines (PANC-1, CFAPC-1, MIA PaCa-2 and ASPC-1), and human pancreatic cell line hTERT-HPNE served as control by real-time PCR. The gene discussed is S100A2; the disease is pancreatic neoplasm.