In two women (20%) an increased activity of aspartate transaminase and alanine transaminase was observed; hyperthyroidism was also observed in 20% of women; likewise, leukopenia and thrombocytopenia were observed in 20% of women, while 10% suffered from asymptomatic leukocyturia and erythrocyturia. The gene discussed is GPT; the disease is hyperthyroidism.