In the whole study cohort, in multivariable analysis, logNT-proBNP (HR 1.03, 95%CI 0.84–1.27, p = 0.77), age (HR 1.02, 95%CI 0.99–1.05, p = 0.29), LVEF (HR 1.02, 95%CI 0.99–1.05, p = 0.19), AF type (HR 0.98, 95%CI 0.63–1.55, p = 0.94), sex (HR 1.04, 95%CI 0.6–1.80, p = 0.89) and baseline systolic pressure (HR 1.02, 95%CI 1.00–1.03, p = 0.08) were not predictors. The gene discussed is NPPB; the disease is atrial fibrillation.