As reported, inhibition of LSD1 restricts herpesvirus infection, shedding, and recurrence, through epigenetic suppression of viral genomes [43], while LSD1 represses influenza A virus infection by erasing monomethylation on lysine 88 of interferon induced transmembrane protein 3 (IFITM3) [40]. This evidence concerns the gene KDM1A and Herpesviridae infectious disease.