RNF213 and multiminicore myopathy: A meta-analysis of five previously published studies [64, 65, 118, 127, 137], including 421 (Chinese/East Asian/Caucasian) patients and 1214 controls for the p.R4810K polymorphism and 398 Japanese patients and 765 controls for the p.R4859K polymorphism confirmed strong associations between the p.R4810K polymorphism of the RNF213 gene and MMD (pooled OR 157.53 vs. 92.03) [138].