Previous work demonstrated that Oxt was anxiolytic when administered to humans (Heinrichs et al., 2003) and rodents (Blume et al., 2008; Ring et al., 2006; Windle et al., 1997), whereas disruption of Oxt gene elevated anxiety level in mice (Amico et al., 2004; Mantella et al., 2003). Here, OXT is linked to Anxiety.