CST3 and nervous system disorder: Among these 52 differentially expressed genes, at least 10 genes are of particular interest: the upregulation of MT1H, CXCR4, PNMT, BTG3, LRP2, AGT, S100B, MAOA and CST3 and the downregulation of CBLN1 have been observed in previous studies investigating PD or other neurological disorders.