Using a series of bioinformatic analysis tools, such as Tumor Immune Estimation Resource (TIMER) (27), Human Protein Atlas project (HPA) (28), and Gene expression profiling analysis (GEPIA) (29), we identified the expression of SMC family members in HCC, and Kaplan-Meier plotter was used to evaluate the prognostic value of SMC family members in HCC. Here, DYM is linked to hepatocellular carcinoma.