Moreover, our results showed that the binding sites of miR-379 within the Igf1r 3′-UTRs and miR-329 within the Dlk1 3′-UTRs were conserved between humans and mice, which further indicated the potential of miR-379/miR-544 cluster as a therapeutic target for human NAFLD. This evidence concerns the gene IGF1R and metabolic dysfunction-associated steatotic liver disease.