H19 and Parkinson disease: Consistently, overexpression of the H19 could prevent dopaminergic neuron loss in the 6-OHDA-induced PD model by activating HPRT1-mediated Wnt/β catenin signaling pathway via impairing miR-301b-3p-targeted repression of HPRT1 transcription (Jiang et al., 2020).