Similarly, exosomal miR-29a and mir-92a were transferred by TEXs to MDSCs in a mouse glioma cell model, and their transfection promoted the expansion of MDSCs by targeting high-mobility group box transcription factor 1 (HBP1) and protein kinase cAMP-dependent type I regulatory subunit alpha (Prkar1a), respectively (Guo et al., 2019). This evidence concerns the gene HBP1 and central nervous system cancer.