In a mouse model of intraosseous prostate cancer, CCL2 signaling was blocked using neutralizing anti-CCL2 antibodies alone or in combination with the chemotherapeutic drug docetaxel; the results indicated that CCL2 blockade inhibits prostate cancer development and the effect is more profound when combined with docetaxel (Kirk et al., 2013). The gene discussed is CCL2; the disease is prostate carcinoma.