NOTCH1 and limb ischemia: Of interest, in a mouse model of limb ischemia, endothelial overexpression of the active form of Notch1 prevents the miR-24-3p-mediated anti-angiogenic effect and, conversely, the inhibition of Notch enhances the anti-angiogenic effect of miR-24-3p, showing that Notch1 is a target of miR-24-3p (Marchetti et al., 2020).