Some researchers have demonstrated that the proliferation and apoptosis of ESCC cells are modulated by several other exosomal cargos, including miRNA-103a-2-5p, miRNA-652-5p, lncRNA Family with sequence similarity 225 member A (FAM225A), and lncRNA urothelial cancer-associated 1 (UCA1) (57, 58, 67, 68). This evidence concerns the gene FAM225A and esophageal squamous cell carcinoma.