The results showed that cell cycle, oocyte meiosis, ubiquitin-mediated proteolysis, RNA degradation, basal transcription factors, progesterone-mediated oocyte maturation, pyrimidine metabolism, NER, spliceosome, p53 signaling pathway, DNA replication, protein export, small cell lung cancer, RNA polymerase, and regulation of autophagy were correlated with the progression of LUAD. This evidence concerns the gene TP53 and small cell lung carcinoma.