These results implied that HMMR gene expression was upregulated in lung adenocarcinoma, bladder urothelial carcinoma, breast invasive carcinoma, clear cell renal cell carcinoma, cholangiocarcinoma, esophageal carcinoma, stomach adenocarcinoma, and others than in their matched adjacent normal tissues. The gene discussed is HMMR; the disease is cholangiocarcinoma.