analyzed more than 400 proteins in stem cell-like pancreatic tumor-initiating cells (TICs) and nontumor-initiating cells (non-TICs) through differential proteomics (PTX) and then nominated S100A8, S100A9, and galactin-3-binding protein LGALS3BP (MAC-2-BP) as putative driver genes for pancreatic TICs, but this conclusion needs further verification (76). The gene discussed is S100A9; the disease is pancreatic neoplasm.