CXCR3 and neoplasm: Moreover, in murine breast cancer models bearing CXCR3 and being induced by IFN-γ, CXCL9 was shown to have the ability to reduce tumour growth and metastatic colonization through recruitment of natural killer (NK) cells and activated T cells (10, 46), exhibiting a better prognosis in the CXCL9-overexpressing group (47).