PLEK2 and metastatic malignant neoplasm in the lymph nodes: We also found a significant association between patients with lymph node metastasis and overexpression of BMP7 (47.4%, P=0.005), CALD1 (42.1%, P=0.020), CDH1 (52.6%, P=0.001), COL3A1 (42.1%, P=0.020), EGFR (47.4%, P=0.005), ERBB3 (57.9%, P=0.000), PLEK2 (47.4%, P=0.024), and TCF4 (52.6%, P=0.001) (see Supplementary Figure S3).