TTR and multiple sclerosis: Some other phytoestrogens which have confirmed neuroprotective impact in vivo and are not as widely known as aforementioned compounds are luteolin (LUT), commonly found in spices like parsley or thyme [92]; chrysin (CHR), a flavonoid that interacts with TTR protein (transthyretin) and thus TTR can play its role and take a part in Aβ clearance [93; 94]; epigallocatechin gallate (EGCG), which is the major polyphenol component of green tea, has confirmed neuroprotective effect in vivo not only in AD but also in amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and PD.