Figure 7F shows the KEGG terms enrichment analysis for the module genes, the genes of MEblue, which were overexpressed in IS1, were mainly involved in the P13/AKT pathway, and genes in MEturquoise upregulated in IS2 were significantly related to the terms of Cell adhesion molecules, and genes of MEgray positively correlated to IS2 mainly participated in Hepatitis C. This evidence concerns the gene AKT1 and hepatitis C virus infection.