NLRP3 and nervous system disorder: In neurological diseases, it has been found that NLRP3 inflammasome is involved in the neuroinflammatory response of Alzheimer’s Disease (AD) (Heneka et al., 2013), ischemic stroke (FANN et al., 2013), multiple sclerosis (Gris et al., 2010) and other diseases, and is closely linked to the development of these diseases (Choi and Ryter, 2014).