KEAP1 and neoplasm: Finally, symmetric dimethylarginine (SDMA) (Fig. 7g), asymmetric dimethylarginine (ADMA) (Fig. 7h) and phenylalanine (Fig. 7i) were markedly increased in tumor compared to peri-tumoral tissue, but these increases were much less pronounced in tumors from either Keap1-KD or Nrf2-KO mice.