Interestingly, ApcMin/+mice that are also deficient for glutathione transferase Pi (Gstp−/−: ApcMin/+) have a 6-fold increase in colon adenoma incidence, and a 50-fold increase in colorectal adenoma multiplicity, in comparison with their Gstp wild-type (Gstp+/+: ApcMin/+) counterparts27. The gene discussed is GSTP1; the disease is colon adenoma.